MST® FOLATE 400 QUATREFOLIC®: Active Folate Generation for Cellular Processes and Reducing Fatigue
MST® Folate 400 Quatrefolic® (90 or 180 capsules) is a premium food supplement, made in Germany (MADE IN GERMANY). It contains the most modern, bioactive form of folate: 400 µg Quatrefolic® per capsule (equivalent to 200% of the Nutrient Reference Values, NRV). If you are looking for where to buy in Germany and want to buy at the best price, this product offers a direct and effective solution. Quatrefolic® is fourth-generation folate in the form of (6S)-5-methyltetrahydrofolic acid (5-MTHF) and was developed to overcome the limitations of conventional folic acid. This product provides a form of vitamin B9 that is directly available to the body and helps support important metabolic and cellular processes.
The Superiority of Quatrefolic® (5-MTHF) over Conventional Folic Acid
Folate (vitamin B9) is an essential micronutrient. Conventional folic acid, a synthetic form, must be converted in the body through a multistep process by the MTHFR enzyme into the biologically active form 5-MTHF [1.2, 1.3].
Bypassing the Metabolic Pathway
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Bioactive Form: Quatrefolic® directly provides active 5-MTHF (glucosamine salt), which is structurally identical to the form naturally occurring in the body [1.3].
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Full Availability: By directly providing 5-MTHF, the often inefficient conversion step involving the MTHFR enzyme is bypassed [1.2]. This is particularly beneficial for people with certain genetic variants (polymorphisms) in whom the conversion of folic acid to 5-MTHF is limited [1.2, 2.5].
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High Stability: Compared with earlier forms of folate, Quatrefolic® demonstrates improved stability and higher water solubility [1.3].
Legally Approved Functions of Folate (According to EU Regulation 432/2012)
The effect of folate on the body has been scientifically confirmed by the European Food Safety Authority (EFSA) and approved for use in food supplements [3.1]:
1. Cellular and Metabolic Processes
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Folate contributes to the reduction of tiredness and fatigue. This is related to its involvement in energy metabolism and normal blood formation [1.5, 3.6].
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Folate contributes to normal amino acid synthesis. Folate in the form of 5-MTHF is a necessary cofactor for the synthesis of nucleic acids and proteins [1.1].
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Folate contributes to normal homocysteine metabolism. 5-MTHF is crucial for the remethylation reaction, in which it converts toxic homocysteine into methionine [2.2, 2.5].
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Folate contributes to normal blood formation. Folate is necessary for the synthesis of DNA and RNA, ensuring the maturation of erythrocytes [1.1].
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Folate has a role in cell division. As a precursor of nucleic acids, folate is required for rapid cell growth and replication [1.1].
2. Specific areas of application
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Folate contributes to normal psychological function. Folate is required for the synthesis of neurotransmitters such as serotonin and dopamine, which influence mood and cognitive processes [1.5].
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Folate contributes to the normal function of the immune system. Folate is necessary for the proliferation of lymphocytes (T cells) during the immune response [1.1].
Benefits of the MST® formulation and dosage
MST® Folate 400 Quatrefolic® offers an optimally dosed, highly pure formulation:
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Critical dosage: Each capsule contains 400 µg of folate in the form of Quatrefolic® (200% NRV), which corresponds to the recommended daily dose for food supplements, particularly in cases of increased requirements.
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Highest bioavailability: Through the direct administration of the active form 5-MTHF, folate is immediately available to the body without having to wait for enzymatic conversion [1.3].
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Premium raw material: Use of the patented branded raw material Quatrefolic® from the 4th generation by Gnosis by Lesaffre.
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MADE IN GERMANY: Guaranteed strict German quality and purity standards.
Detailed overview of the ingredients and dosage (per 1 capsule - daily dose)
| Ingredient (ingredients) | Per capsule | % NRV* |
| Folic acid Quatrefolic® (folic acid Quatrefolic®) | 400 µg | 200% |
*NRV = % of nutrient reference values (according to Regulation (EU) No. 1169/2011)
Excipients: (According to the original packaging, e.g. filler, HPMC capsule shell, etc.)
Consumption recommendations and information
Recommended dosage:
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Take 1 capsule daily.
Dosage schedule:
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The capsule should be taken daily with sufficient water.
Important information (EU-compliant):
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The recommended daily intake must not be exceeded.
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Food supplements are not a substitute for a balanced, varied diet and a healthy lifestyle.
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Consultation with a specialist: People taking medication should consult a specialist before use.
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Storage: Keep out of reach of young children.
Where to buy MST® FOLATE 400 QUATREFOLIC®: Availability in Germany and the EU
You can purchase MST Folate 400 Quatrefolic® directly from the manufacturer. This guarantees premium quality and compliance with European standards.
If you want to buy Folate Quatrefolic® at the best price in Europe, choose the official source. The product is available in Germany, including the following major cities:
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Berlin (Berlin)
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Hamburg (Hamburg)
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Munich (Munich)
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Cologne (Cologne)
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Frankfurt am Main (Frankfurt am Main)
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Official manufacturer's website (90 capsules): Folate 400 Quatrefolic® 90 capsules
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Official manufacturer's website (180 capsules): Folate 400 Quatrefolic® 180 capsules
Conclusion
MST® Folate 400 Quatrefolic® offers an intelligent and modern approach to supplementing the body's folate stores. By using the active form 5-MTHF, the product ensures high bioavailability and effectiveness, regardless of individual metabolic characteristics such as MTHFR polymorphism. Given folate's proven role in reducing tiredness, supporting immune and psychological function, and normalizing homocysteine, MST® Folate 400 Quatrefolic® is a reliable choice for daily support of bodily functions that meets all strict European quality and safety requirements.
Research sources
[1.1] Folate Role and Recognized EFSA claims - Quatrefolic (Quatrefolic overview and EFSA claims on cell division, amino acid synthesis, blood formation, and immune function).
[1.2] Folate VS. Folic Acid - Quatrefolic (MTHFR polymorphism and active folate form).
[1.3] About folate - Quatrefolic (5-MTHF, stability, and MTHFR bypass).
[1.5] Folate contributes to psychological function and homocysteine metabolism (Review on B vitamins and cognition).
[2.2] Molecular Biology of Methylenetetrahydrofolate Reductase (MTHFR) and Overview of Mutations/Polymorphisms - NCBI (MTHFR role in homocysteine metabolism).
[2.5] MTHFR gene: MedlinePlus Genetics (MTHFR role in homocysteine and folate processing).
[3.1] Commission Regulation (EU) No 432/2012 (List of permitted health claims).
[3.6] Folate contributes to the reduction of tiredness and fatigue (EFSA claim).








